Blar i NILU Brage på forfatter "Mariussen, Espen"

Viser treff 1-20 av 23

    • A survey of dioxin-like contaminants in fish from recreational fishing. 

      Heimstad, Eldbjørg Sofie; Grønstøl, Gaute; Hetland, Karl Torstein; Alarcon, Javier Martinez; Rylander, Charlotta; Mariussen, Espen (Journal article; Peer reviewed, 2015)

    • Advanced Respiratory Models for Hazard Assessment of Nanomaterials. Performance of Mono-, Co- and Tricultures 

      Camassa, Laura Maria Azzurra; Elje, Elisabeth; Mariussen, Espen; Longhin, Eleonora Marta; Dusinska, Maria; Zienolddiny-Narui, Shanbeh; Rundén-Pran, Elise (Peer reviewed; Journal article, 2022)
      Advanced in vitro models are needed to support next-generation risk assessment (NGRA), moving from hazard assessment based mainly on animal studies to the application of new alternative methods (NAMs). Advanced models must ...

    • BHT i kosmetiske produkter. 

      Schlabach, Martin; Dye, Christian; Gundersen, Hans; Enge, Ellen Katrin; Mariussen, Espen (NILU OR;35/2005, Research report, 2005)
      På oppdrag av Mattilsynet, Nasjonalt senter, Sandnes har Norsk institutt for luftforskning (NILU) kartlagt forekomsten av BHT i forskjellige kosmetiske produkter. Alle prøvene ble tatt av Mattilsynet. BHT brukes som ...

    • Clinical application of intrathecal gadobutrol for assessment ofcerebrospinal fluid tracer clearance to blood 

      Eide, Per Kristian; Mariussen, Espen; Uggerud, Hilde Thelle; Pripp, Are Hugo; Lashkarivand, Aslan; Hassel, Bjørnar; Christensen, Hege Staaland; Hovd, Markus Herberg; Ringstad, Geir Andre (Peer reviewed; Journal article, 2021)
      BACKGROUND. Methodology for estimation of cerebrospinal fluid (CSF) tracer clearance could have wide clinical application in predicting excretion of intrathecal drugs and metabolic solutes from brain metabolism and for ...

    • The colony forming efficiency assay for toxicity testing of nanomaterials – Modifications for higher-throughput 

      Rundén-Pran, Elise; Mariussen, Espen; El Yamani, Naouale; Elje, Elisabeth; Longhin, Eleonora Marta (Peer reviewed; Journal article, 2022)
      To cope with the high number of nanomaterials manufactured, it is essential to develop high-throughput methods for in vitro toxicity screening. At the same time, the issue with interference of the nanomaterial (NM) with ...

    • Contaminants in fish from Etnefjord, Norway 

      Mariussen, Espen; Schlabach, Martin (NILU OR;50/2011, Research report, 2011)
      1,2,5,6,9,10-hexabromocyclododecane (HBCDD) is one of the most frequently used brominated flame retardants (BFR) and is considered as an emerging environmental pollutant. Recently, high levels of HBCDD were reported in ...

    • Contaminants in fish from Etnefjord, Norway. 

      Mariussen, Espen; Schlabach, Martin (NILU OR;50/2011, Research report, 2011)
      1,2,5,6,9,10-hexabromocyclododecane (HBCDD) is one of the most frequently used brominated flame retardants (BFR) and is considered as an emerging environmental pollutant. Recently, high levels of HBCDD were reported in ...

    • Different Sensitivity of Advanced Bronchial and Alveolar Mono- and Coculture Models for Hazard Assessment of Nanomaterials 

      Elje, Elisabeth; Mariussen, Espen; McFadden, Erin; Dusinska, Maria; Rundén-Pran, Elise (Peer reviewed; Journal article, 2023)
      For the next-generation risk assessment (NGRA) of chemicals and nanomaterials, new approach methodologies (NAMs) are needed for hazard assessment in compliance with the 3R’s to reduce, replace and refine animal experiments. ...

    • Fluorescent Nanocomposites: Hollow Silica Microspheres with Embedded Carbon Dots 

      Delic, Asmira; Mariussen, Espen; Roede, Erik Dobloug; Krivokapic, Alexander; Erbe, Andreas; Lindgren, Mikael; Benelmekki, Maria; Einarsrud, Mari-Ann (Peer reviewed; Journal article, 2021)
      Intrinsically fluorescent carbon dots may form the basis for a safer and more accurate sensor technology for digital counting in bioanalytical assays. This work presents a simple and inexpensive synthesis method for producing ...

    • Fluorescent Nanocomposites: Hollow Silica Microspheres with Embedded Carbon Dots 

      Delic, Asmira; Mariussen, Espen; Roede, Erik Dobloug; Krivokapic, Alexander; Erbe, Andreas; Lindgren, Mikael; Benelmekki, Maria; Einarsrud, Mari-Ann (Peer reviewed; Journal article, 2021)
      Intrinsically fluorescent carbon dots may form the basis for a safer and more accurate sensor technology for digital counting in bioanalytical assays. This work presents a simple and inexpensive synthesis method for producing ...

    • Genotoxicity of Nanomaterials: Advanced In Vitro Models and High Throughput Methods for Human Hazard Assessment - A Review 

      Kohl, Yvonne; Rundén-Pran, Elise; Mariussen, Espen; Hesler, Michelle; El Yamani, Naouale; Longhin, Eleonora Marte; Dusinska, Maria (Peer reviewed; Journal article, 2020)
      Changes in the genetic material can lead to serious human health defects, as mutations in somatic cells may cause cancer and can contribute to other chronic diseases. Genotoxic events can appear at both the DNA, chromosomal ...

    • Hazard identification of nanomaterials: In silico unraveling of descriptors for cytotoxicity and genotoxicity 

      El Yamani, Naouale; Mariussen, Espen; Gromelski, Maciej; Wyrzykowska, Ewelina; Grabarek, Dawid; Puzyn, Tomasz; Tanasescu, Speranta; Dusinska, Maria; Rundén-Pran, Elise (Peer reviewed; Journal article, 2022)
      Hazard identification and safety assessment of the huge variety of nanomaterials (NMs), calls for robust and validated toxicity screening tests in combination with cheminformatics approaches to identify factors that can ...

    • Hepato(Geno)Toxicity Assessment of Nanoparticles in a HepG2 Liver Spheroid Model 

      Elje, Elisabeth; Mariussen, Espen; Moriones, Oscar H.; Bastus, Neus G.; Puntes, Victor; Kohl, Yvonne; Dusinska, Maria; Rundén-Pran, Elise (Peer reviewed; Journal article, 2020)
      (1) In compliance with the 3Rs policy to reduce, refine and replace animal experiments, the development of advanced in vitro models is needed for nanotoxicity assessment. Cells cultivated in 3D resemble organ structures ...

    • Kartlegging av bromerte flammehemmere og klorerte parafiner. 

      Schlabach, Martin; Mariussen, Espen; Borgen, Anders; Dye, Christian; Enge, Ellen Katrin; Steinnes, Eiliv; Green, Norman; Mohn, Henning (NILU OR;62/2002, Research report, 2002)
      NILU har på oppdrag fra SFT gjennomført en screening-undersøkelse av de mest relevante bromerte flammehemmere (BFR) og klorerte parafiner (CP) fra utvalgte deler av det norske miljøet. Det ble fokusert påutlekking fra ...

    • Microfluidic In Vitro Platform for (Nano)Safety and (Nano)Drug Efficiency Screening 

      Kohl, Yvonne; Biehl, Margit; Spring, Sarah; Hesler, Michelle; Ogourtsov, Vladimir; Todorovic, Miomir; Owen, Joshua; Elje, Elisabeth; Kopecka, Kristina; Moriones, Oscar Hernando; Bastus, Neus G.; Simon, Peter; Dubaj, Tibor; Rundén-Pran, Elise; Puntes, Victor; William, Nicola; von Briesen, Hagen; Wagner, Sylvia; Kapur, Nikil; Mariussen, Espen; Nelson, Andrew; Gabelova, A; Dusinska, Maria; Velten, Thomas; Knoll, Thorsten (Peer reviewed; Journal article, 2021)
      Microfluidic technology is a valuable tool for realizing more in vitro models capturing cellular and organ level responses for rapid and animal‐free risk assessment of new chemicals and drugs. Microfluidic cell‐based devices ...

    • NanoSolveIT Project: Driving nanoinformatics research to develop innovative and integrated tools for in silico nanosafety assessment 

      Afantitis, Antreas; Melagraki, Georgia; Isigonis, Panagiotis; Tsoumanis, Andreas; Varsou, Dimitra Danai; Valsami-Jones, Eugenia; Papadiamantis, Anastasios; Ellis, Laura-Jayne; Sarimveis, Haralambos; Doganis, Philip; Karatzas, Pantelis; Tsiros, Periklis; Liampa, Irene; Lobaskin, Vladimir; Greco, Dario; Serra, Angela; Kinaret, Pia Anneli Sofia; Saarimaki, Laura Aliisa; Grafström, Roland; Kohonen, Pekka; Nymark, Penny; Willighagen, Egon; Puzyn, Tomasz; Rybinska-Fryca, Anna; Lyubartsev, Alexander; Jensen, Keld Alstrup; Brandenburg, Gerit; Lofts, Stephen; Svendsen, Claus; Harrison, Samuel; Maier, Dieter; Tamm, Kaido; Janes, Jaak; Sikk, Lauri; Dusinska, Maria; Longhin, Eleonora Marte; Rundén-Pran, Elise; Mariussen, Espen; El Yamani, Naouale; Unger, Wolfgang; Radnik, Jörg; Tropsha, Alexander; Cohen, Yoram; Leszcynski, Jerzy; Hendren, Christine Ogilvie; Wiesner, Mark; Winkler, David; Suzuki, Noriyuki; Yoon, Tae Hyun; Choi, Jang-Sik; Gulumian, Mary; Lynch, Iseult (Peer reviewed; Journal article, 2020)
      Nanotechnology has enabled the discovery of a multitude of novel materials exhibiting unique physicochemical (PChem) properties compared to their bulk analogues. These properties have led to a rapidly increasing range of ...

    • Population pharmacokinetic modeling of CSF to blood clearance: prospective tracer study of 161 patients under work-up for CSF disorders 

      Hovd, Markus Herberg; Mariussen, Espen; Uggerud, Hilde Thelle; Lashkarivand, Aslan; Christensen, Hege; Ringstad, Geir; Eide, Per Kristian (Peer reviewed; Journal article, 2022)
      Background Quantitative measurements of cerebrospinal fluid to blood clearance has previously not been established for neurological diseases. Possibly, variability in cerebrospinal fluid clearance may affect the underlying ...

    • Population pharmacokinetic modeling of CSF to blood clearance: prospective tracer study of 161 patients under work-up for CSF disorders 

      Hovd, Markus Herberg; Mariussen, Espen; Uggerud, Hilde Thelle; Lashkarivand, Aslan; Christensen, Hege; Ringstad, Geir; Eide, Per Kristian (Peer reviewed; Journal article, 2022)
      Background Quantitative measurements of cerebrospinal fluid to blood clearance has previously not been established for neurological diseases. Possibly, variability in cerebrospinal fluid clearance may affect the underlying ...

    • Safe(r) by design implementation in the nanotechnology industry 

      Jiménes, Araceli Sánchez; Puelles, Raquel; Pérez-Fernández, Marta; Gómez-Fernández, Paloma; Barruetabena, Leire; Jacobsen, Nicklas Raun; Suarez-Merino, Blanca; Micheletti, Christian; Manier, Nicolas; Trouiller, Benedicte; Navas, José Maria; Kalman, Judit; Salieri, Beatrice; Hischier, Roland; Handzhiyski, Yordan; Apostolova, Margarita D.; Hadrup, Niels; Bouillard, Jaques; Oudart, Yohan; Merino, Cesar; Garcia, Erika; Liguori, Biase; Sabella, Stefania; Rose, Jerome; Maison, Armand; Galea, Karen S.; Kelly, Sean; Stepankova, Sandra; Mouneyrac, Catherine; Barrick, Andrew; Chatel, Amelie; Dusinska, Maria; Rundén-Pran, Elise; Mariussen, Espen; Bressot, Christophe; Aguerre-Chariol, Olivier; Shandilya, Neeraj; Goede, Henk; Gomez-Cordon, Julio; Simar, Sophie; Nesslany, Fabrice; Jensen, Keld Alstrup; van Tongeren, Martie; Llopis, Isabel Rodriguez (Peer reviewed; Journal article, 2020)
      The implementation of Safe(r) by Design (SbD) in industrial innovations requires an integrated approach where the human, environmental and economic impact of the SbD measures is evaluated across and throughout the nanomaterial ...

    • The comet assay applied to HepG2 liver spheroids 

      Elje, Elisabeth; Hesler, Michelle; Rundén-Pran, Elise; Mann, Pascal; Mariussen, Espen; Wagner, Sylvia; Dusinska, Maria; Kohl, Yvonne (Journal article; Peer reviewed, 2019)
      In accordance with the 3 Rs to reduce in vivo testing, more advanced in vitro models, moving from 2D monolayer to 3D cultures, should be developed for prediction of human toxicity of industrial chemicals and environmental ...